“Identification and Characterization of Aconitum napellus L. (Tubers) for Anti-Arthritic Activity”

Khalure Pallavi Ravishankar, Phool Singh Yaduwanshi, Jyotiram A Sawale, Kavita Loksh, Manojkumar Solanki, Rashmi Shrivastava
Page No: 113-139
DOI: 10.86493/OTJ.25341212
Download PDFAbstract:
The increasing prevalence of arthritis and limitations associated with conventional therapies have led to growing interest in plant-based alternatives. Aconitum napellus L., a medicinal plant belonging to the Ranunculaceae family, has long been used in traditional medicine for its analgesic and anti-inflammatory properties. The present study focuses on the identification, Pharmacognostic characterization, phytochemical evaluation, and anti-arthritic potential of Aconitum napellus tubers. The plant material was subjected to macroscopic and microscopic analysis, followed by extraction using hydroalcoholic solvents. Preliminary phytochemical screening confirmed the presence of alkaloids, flavonoids, glycosides, and phenolic compounds. The anti-arthritic activity was evaluated using in vitro models including protein denaturation inhibition and membrane stabilization assays. The results demonstrated significant dosedependent inhibition of protein denaturation and stabilization of erythrocyte membranes, indicating potential anti-inflammatory effects. The findings suggest that Aconitum napellus may serve as a promising candidate for the development of anti-arthritic agents. However, due to the presence of toxic alkaloids, further safety and toxicity studies are necessary before clinical appl

Citations

APA: Khalure Pallavi Ravishankar, Phool Singh Yaduwanshi, Jyotiram A Sawale, Kavita Loksh, Manojkumar Solanki, Rashmi Shrivastava (2026). “Identification and Characterization of Aconitum napellus L. (Tubers) for Anti-Arthritic Activity”. DOI: 10.86493/OTJ.25341212

AMA: Khalure Pallavi Ravishankar, Phool Singh Yaduwanshi, Jyotiram A Sawale, Kavita Loksh, Manojkumar Solanki, Rashmi Shrivastava. “Identification and Characterization of Aconitum napellus L. (Tubers) for Anti-Arthritic Activity”. 2026. DOI: 10.86493/OTJ.25341212

Chicago: Khalure Pallavi Ravishankar, Phool Singh Yaduwanshi, Jyotiram A Sawale, Kavita Loksh, Manojkumar Solanki, Rashmi Shrivastava. "“Identification and Characterization of Aconitum napellus L. (Tubers) for Anti-Arthritic Activity”." Published 2026. DOI: 10.86493/OTJ.25341212

IEEE: Khalure Pallavi Ravishankar, Phool Singh Yaduwanshi, Jyotiram A Sawale, Kavita Loksh, Manojkumar Solanki, Rashmi Shrivastava, "“Identification and Characterization of Aconitum napellus L. (Tubers) for Anti-Arthritic Activity”," 2026, DOI: 10.86493/OTJ.25341212

ISNAD: Khalure Pallavi Ravishankar, Phool Singh Yaduwanshi, Jyotiram A Sawale, Kavita Loksh, Manojkumar Solanki, Rashmi Shrivastava. "“Identification and Characterization of Aconitum napellus L. (Tubers) for Anti-Arthritic Activity”." DOI: 10.86493/OTJ.25341212

MLA: Khalure Pallavi Ravishankar, Phool Singh Yaduwanshi, Jyotiram A Sawale, Kavita Loksh, Manojkumar Solanki, Rashmi Shrivastava. "“Identification and Characterization of Aconitum napellus L. (Tubers) for Anti-Arthritic Activity”." 2026, DOI: 10.86493/OTJ.25341212